New from PDHC!
This Chronicle marks the beginning of a shared journey to 𝗲𝘅𝗽𝗹𝗼𝗿𝗲 𝗯𝗼𝗹𝗱 𝗶𝗱𝗲𝗮𝘀, 𝗰𝗼𝗻𝗻𝗲𝗰𝘁 𝗮𝗰𝗿𝗼𝘀𝘀 𝗱𝗶𝘀𝗰𝗶𝗽𝗹𝗶𝗻𝗲𝘀, and 𝗯𝘂𝗶𝗹𝗱 𝗮𝗻 𝗲𝗰𝗼𝘀𝘆𝘀𝘁𝗲𝗺 where groundbreaking medicines can emerge.
Recent clinical and regulatory advances underscore a rapidly accelerating peptide therapeutics landscape, driven by…
Combinatorial chemistry has transformed the discovery of bioactive molecules by enabling the rapid generation and…
The discovery of high-affinity cyclic peptides against predefined targets remains intrinsically difficult. What slows progress is…
Most fundamental advances are not planned—they emerge when the conditions are right. When smaller steps forward are required…
PDHC has a responsibility, to evolve from a volunteer-driven community into a durable platform with clear leadership, sustainable funding, and shared accountability.
On behalf of the entire PDHC, especially those who have contributed as authors, editorial reviewers, and our publishing team, we enthusiastically welcome you…
Looking ahead, we anticipate a marked increase in clinical readouts and impactful peptide-related advancements…
The Evolution of Catch-and-Release Purification
ON THE DISCOVERY OF MK-0616 (ENLICITIDE), A NOVEL ORAL MACROCYCLIC PEPTIDE PCSK9 INHIBITOR…
Potency is a key driver of therapeutic success, but even highly potent peptides often stumble at the clinic-translation step…
Peptides have evolved from biochemical tools into a major class of therapeutic agents propelled by the success of drugs such as semaglutide and tirzepatide…
Leadership is often associated with authority and control, but in consultancy it takes a different form…
Pumpkins have long been valued not only as a staple of fall traditions but also for their medicinal seeds…
We hope this marks the beginning of an adventure that is both inspiring and catalytic…
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